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Jurisdiction JJ Lab Billing Guide

The Medicare Part B billing reference for laboratories in Alabama, Georgia, Tennessee; MolDX Z-Code rules, LCDs, frequency limits, TPE audit trends, and enrollment requirements, from TransLabs.
Jurisdiction JJ
STATES / TERRITORIES PHONE · PORTAL CLAIM VOLUME BENEFICIARIES
1-855-252-8782 · Novitasphere JL ~200 million claims/year ~3.4 million Medicare FFS
STATES / TERRITORIES
PHONE · PORTAL
1-855-252-8782 · Novitasphere JL
CLAIM VOLUME
~200 million claims/year
BENEFICIARIES
~3.4 million Medicare FFS
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Jurisdiction about us

Overview

JJ is administratively the most important MAC jurisdiction for molecular diagnostic labs nationwide, because Palmetto GBA administers the MolDX program, the national coverage review system for molecular diagnostic tests; from its JJ base. Palmetto issues DEX Z-Codes that apply across all seven MolDX jurisdictions (JE, JF, J5, J8, J15, JJ, JM). For labs billing molecular tests, Palmetto is therefore a critical regulatory relationship regardless of which MAC jurisdiction the lab is physically located in.

MolDX and Z-Code Requirements

JJ is a MolDX jurisdiction, and Palmetto GBA is the program’s originating administrator. Any lab billing molecular diagnostic tests, CPT codes in the 81XXX range, or most PLA codes needs an active DEX Z-Code from Palmetto GBA’s DEX platform (dexzcodes.com) registered before those claims go out the door.

GOVERNING LCD

LCD L35025 — MolDX: Molecular Diagnostic Tests (MDT) — originates with Palmetto and governs coverage for hereditary cancer panels, pharmacogenomics, somatic tumor profiling, NGS, BRCA/BRCA2, Lynch syndrome, and PLA-coded tests across all seven MolDX jurisdictions.

WHY IT MATTERS

Claims without a valid Z-Code are denied automatically, with no manual override at the claims level. Because Palmetto originates MolDX coverage decisions nationally, keeping your Z-Code registrations current here has consequences well beyond JJ’s three states.

Key Lab LCDs in This Jurisdiction

These coverage areas drive the majority of routine lab denials in JJ. LCD numbers move as the contractor retires and reissues policies, so confirm each one in the Medicare Coverage Database before citing it in a claim or appeal.
LCD Coverage Area Key Requirement
L35025 MolDX: Molecular Diagnostic Tests (MDT) Palmetto is the originating MAC for all MolDX coverage decisions, including hereditary cancer panels, pharmacogenomics, somatic tumor profiling, NGS, BRCA/BRCA2, Lynch syndrome, and PLA-coded tests.
L35062 Glycated Hemoglobin (HbA1c) Standard quarterly policy. Georgia and Alabama have high diabetes prevalence.
L34752 Urine Drug Testing Active LCD. Tennessee's opioid crisis has made drug testing billing a significant compliance area in JJ.
L35396 Tumor Markers Active enforcement. Georgia's oncology market is growing — tumor marker billing is a significant revenue and compliance area.
L35095 Vitamin D Assay Standard documentation requirements.

Frequency Limits — Top Lab Tests

Frequency violations are one of the most common, and most avoidable, reasons JJ claims get denied or clawed back on audit.
Test CPT Frequency Limit
Molecular tests (Z-Code covered) 81XXX range Frequency is specified in each MolDX Z-Code coverage determination — varies by test and clinical context
HbA1c 83036 Standard quarterly framework
Drug Testing 80305-80307 / G0480-G0483 Per written clinical protocol with documented medical necessity
Tumor markers (general) 82378/86304/etc. Standard quarterly/surveillance framework

TPE Audit Activity

TPE activity in JJ runs high, particularly for two categories:

Molecular diagnostics — MolDX compliance, given Palmetto’s direct oversight of the national program from this jurisdiction.

Drug testing — Tennessee’s opioid crisis has made this a significant, ongoing focus area.

GET AHEAD OF IT

Because Palmetto administers MolDX nationally, its own jurisdiction sees a disproportionate share of Z-Code-related review activity. Labs in JJ billing molecular tests should treat Z-Code maintenance as an ongoing process, not a one-time registration.

Practical Lab Billing Notes

MOLDX ADMINISTRATOR:

Palmetto GBA’s MolDX team is the authoritative body for all molecular diagnostic test coverage across all seven MolDX jurisdictions. Labs anywhere in JE, JF, J5, J8, J15, JJ, or JM that bill molecular tests must have a direct relationship with Palmetto’s MolDX program through dexzcodes.com.

DEX Z-Code process:

submit a Test Coverage Review (TCR) for each molecular test in your catalog, including peer-reviewed clinical evidence, intended clinical use, CPT code(s), and lab accreditation. Palmetto typically takes 90-180 days for new test reviews.

Palmetto is also the HH+H MAC for JM

giving Palmetto a uniquely broad Medicare footprint.

Tennessee labs billing drug testing

should review CGS J15 practices as a model — similar opioid-crisis-driven scrutiny applies.

Atlanta, GA is a major genomics and molecular diagnostics market

lab billing here requires current MolDX coverage and proactive Z-Code maintenance.
Jurisdiction

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Provider Enrollment, ABN & CLFS

Area Requirement
Provider Enrollment CMS-855B to the Palmetto GBA Provider Enrollment unit in Columbia, SC.
ABN Requirements Critical for molecular testing — Palmetto requires ABN documentation for any molecular test without confirmed Z-Code coverage or where the coverage determination has expired.
CLFS / Fee Schedule Palmetto GBA is proactive in publishing CLFS impact notices given the molecular testing market in its jurisdictions.

Stop Leaving Laboratory Reimbursements on the Table

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Frequently Asked Questions

Is Jurisdiction JJ a MolDX jurisdiction?

Yes, and Palmetto GBA is the program's originating administrator; Palmetto issues the DEX Z-Codes used across all seven MolDX jurisdictions. Labs billing molecular tests in JJ must hold an active Z-Code before submitting claims.

What happens if a lab bills a molecular test in JJ without a Z-Code?

The claim is denied automatically. There's no manual override at the claims level, which is why Z-Code registration has to happen before billing.

Which states does Jurisdiction JJ cover?

Alabama, Georgia, and Tennessee. Palmetto also administers JM (North Carolina, South Carolina, Virginia, West Virginia) through the same provider portal.

Why does Palmetto GBA matter to labs outside JJ and JM?

Palmetto's MolDX program issues the Z-Codes used across all seven MolDX jurisdictions; JE, JF, J5, J8, J15, JJ, and JM, so any lab billing molecular tests in those jurisdictions has a direct relationship with Palmetto through dexzcodes.com, regardless of physical location.

How often can HbA1c be billed under JJ?

Quarterly for stable diabetic patients. More frequent billing needs documentation of a treatment change or new diagnosis.

What form is used for independent lab enrollment in JJ?

CMS-855B, submitted to the Palmetto GBA Provider Enrollment unit in Columbia, SC.

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